LIMA1 Chromosome 12

LIM domain and actin binding 1
2 variants 2 Health Risk

Upload your DNA to see your personal genotypes for variants in LIMA1.

What This Gene Does
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]
Gene Info
Gene Group
"LIM domain containing|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
12q13.12
Ensembl
ENSG00000050405
Associated Conditions (1)
LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 8
Key Variants
All Variants (2)
RSID Category Clinical Significance Conditions
RS140372565 Health Risk association LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 8, LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 8
RS1555205375 Health Risk association LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 8, LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 8
Sign Up to Analyze Your DNA Log In