KIF24 Chromosome 9
Kinesin family member 24
Upload your DNA to see your personal genotypes for variants in KIF24.
What This Gene Does
This gene encodes a member of the kinesin superfamily of microtubule-based motor proteins which are involved in the intracellular transport of membranous organelles, protein complexes, and mRNAs. They also play critical roles in mitosis, morphogenesis, and signal transduction. The encoded protein contains an N-terminal sterile alpha motif (SAM) domain and an ATP-binding kinesin motor domain. It binds centriolar coiled coil protein 110 and centrosomal protein 97 and localizes to the mother centriole to regulate ciliogenesis by controlling microtubule polymerization. [provided by RefSeq, Mar 2017]
Gene Info
Gene Group
"Kinesins|Sterile alpha motif domain containing|Small nucleolar RNA protein coding host genes"
Locus Type
gene with protein product
Location
9p13.3
Ensembl
ENSG00000186638
Associated Conditions (1)
Asphyxiating thoracic dystrophy 3
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS535585536 | Health Risk | Pathogenic | Asphyxiating thoracic dystrophy 3, Asphyxiating thoracic dystrophy 3 |