KIF15 Chromosome 3
Kinesin family member 15
Upload your DNA to see your personal genotypes for variants in KIF15.
What This Gene Does
Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in centrosome separation; microtubule-based movement; and mitotic spindle assembly. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Kinesins
Locus Type
gene with protein product
Location
3p21.31
Ensembl
ENSG00000163808
Associated Conditions (2)
Braddock-carey syndrome 2
Pulmonary fibrosis
Key Variants
RS112882527
Conflicting classifications of pathogenicity
Health Risk
RS2529223639
Likely pathogenic
Braddock-carey syndrome 2, Braddock-carey syndrome 2
Health Risk
RS1182846113
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS1247963130
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS1296637776
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS201923210
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS2528970315
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS2529061466
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS2529198611
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS549556281
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS758022463
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
RS777570812
Likely risk allele
Pulmonary fibrosis, Pulmonary fibrosis
Health Risk
All Variants (14)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS112882527 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS2529223639 | Health Risk | Likely pathogenic | Braddock-carey syndrome 2, Braddock-carey syndrome 2 |
| RS1182846113 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS1247963130 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS1296637776 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS201923210 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS2528970315 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS2529061466 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS2529198611 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS549556281 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS758022463 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS777570812 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS779615762 | Health Risk | Likely risk allele | Pulmonary fibrosis, Pulmonary fibrosis |
| RS1002572191 | Health Risk | Pathogenic | Braddock-carey syndrome 2, Braddock-carey syndrome 2 |