IRAK1 Chromosome X
Interleukin 1 receptor associated kinase 1
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What This Gene Does
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Interleukin 1 receptor associated kinase family
Locus Type
gene with protein product
Location
Xq28
Ensembl
ENSG00000184216
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS202066173 | Health Risk | Conflicting classifications of pathogenicity | — |