IL1RL2 Chromosome 2
Interleukin 1 receptor like 2
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What This Gene Does
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing"
Locus Type
gene with protein product
Location
2q12.1
Ensembl
ENSG00000115598
Associated Conditions (1)
Ascending aortic dissection
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS10167431 | Health Risk | association | Ascending aortic dissection, Ascending aortic dissection |
| RS2241132 | Health Risk | association | Ascending aortic dissection, Ascending aortic dissection |