IL17F Chromosome 6
Interleukin 17F
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What This Gene Does
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Interleukins
Locus Type
gene with protein product
Location
6p12.2
Ensembl
ENSG00000112116
Associated Conditions (5)
Candidiasis
familial
6
Familial pancreatic carcinoma
Gastric cancer
Key Variants
RS1015495067
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS11465552
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS117796773
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS1345707985
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS141798304
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS144854652
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS145598353
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS201102127
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS569473195
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
RS769617558
Conflicting classifications of pathogenicity
Candidiasis, familial, 6
Health Risk
All Variants (10)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1015495067 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS11465552 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS117796773 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS1345707985 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS141798304 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS144854652 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS145598353 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS201102127 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS569473195 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |
| RS769617558 | Health Risk | Conflicting classifications of pathogenicity | Candidiasis, familial, 6 |