IGKC Chromosome 2
Immunoglobulin kappa constant
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What This Gene Does
Predicted to enable antigen binding activity. Involved in adaptive immune response. Located in blood microparticle and extracellular exosome. Part of IgG immunoglobulin complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Immunoglobulin kappa locus at 2p11.2
Locus Type
immunoglobulin gene
Location
2p11.2
Ensembl
ENSG00000211592
Associated Conditions (1)
Recurrent infections associated with rare immunoglobulin isotypes deficiency
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2528720999 | Health Risk | Pathogenic | Recurrent infections associated with rare immunoglobulin isotypes deficiency, Recurrent infections associated with rare immunoglobulin isotypes deficiency, Recurrent infections associated with rare immunoglobulin isotypes deficiency |