IFITM3 Chromosome 11

Interferon induced transmembrane protein 3
1 variant 1 Health Risk

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What This Gene Does
Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 and belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2. [provided by RefSeq, Nov 2021]
Gene Info
Gene Group
"Interferon induced transmembrane protein family|Dispanins"
Locus Type
gene with protein product
Location
11p15.5
Ensembl
ENSG00000142089
Associated Conditions (3)
Influenza
severe
susceptibility to
Key Variants
RS12252
risk factor
Influenza, severe, susceptibility to
Health Risk
All Variants (1)
RSID Category Clinical Significance Conditions
RS12252 Health Risk risk factor Influenza, severe, susceptibility to
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