HSF2BP Chromosome 21
Heat shock transcription factor 2 binding protein
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What This Gene Does
HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Armadillo like helical domain containing|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
21q22.3
Ensembl
ENSG00000160207
Associated Conditions (1)
Premature ovarian failure 19
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1319345920 | Health Risk | Likely pathogenic | Premature ovarian failure 19, Premature ovarian failure 19 |
| RS781780538 | Health Risk | Likely pathogenic | Premature ovarian failure 19, Premature ovarian failure 19 |