HCRTR2 Chromosome 6
Hypocretin receptor 2
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What This Gene Does
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
Gene Info
Gene Group
Hypocretin receptors
Locus Type
gene with protein product
Location
6p12.1
Ensembl
ENSG00000137252
Associated Conditions (1)
HCRTR2-related disorder
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS141299250 | Health Risk | Conflicting classifications of pathogenicity | HCRTR2-related disorder, HCRTR2-related disorder |