H2BW2 Chromosome X
H2B.W histone 2
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What This Gene Does
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family. [provided by RefSeq, Nov 2015]
Gene Info
Gene Group
H2B histones
Locus Type
gene with protein product
Location
Xq22.2
Ensembl
ENSG00000101812
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS782616912 | Health Risk | Conflicting classifications of pathogenicity | — |