GGN Chromosome 19

Gametogenetin

2 variants 2 Health Risk

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What This Gene Does

This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

Associated Conditions (1)

Spermatogenic failure 69

Key Variants

RS2145140504

Pathogenic

Spermatogenic failure 69, Spermatogenic failure 69

Health Risk

RS751658286

Pathogenic

Spermatogenic failure 69, Spermatogenic failure 69

Health Risk

All Variants (2)

RSID	Category	Clinical Significance	Conditions
RS2145140504	Health Risk	Pathogenic	Spermatogenic failure 69, Spermatogenic failure 69
RS751658286	Health Risk	Pathogenic	Spermatogenic failure 69, Spermatogenic failure 69