FYN Chromosome 6

FYN proto-oncogene, Src family tyrosine kinase

2 variants 2 Health Risk

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What This Gene Does

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]

Gene Info

Gene Group

"SH2 domain containing|Src family tyrosine kinases"

Locus Type

gene with protein product

Location

6q21

Ensembl

ENSG00000010810

Associated Conditions (1)

EBV-positive nodal T- and NK-cell lymphoma

Key Variants

RS1351655525

Pathogenic

EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma

Health Risk

RS370573757

Pathogenic

EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma

Health Risk

All Variants (2)

RSID	Category	Clinical Significance	Conditions
RS1351655525	Health Risk	Pathogenic	EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma
RS370573757	Health Risk	Pathogenic	EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma