FUT2 Chromosome 19
Fucosyltransferase 2 (H blood group)
Upload your DNA to see your personal genotypes for variants in FUT2.
What This Gene Does
This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. The encoded protein is important for the final step in the soluble ABO blood group antigen synthesis pathway. It is also involved in cell-cell interaction, cell surface expression, and cell proliferation. Mutations in this gene are a cause of the H-Bombay blood group where red blood cells lack the H antigen. [provided by RefSeq, May 2022]
Gene Info
Gene Group
"Fucosyltransferases|Blood group antigens"
Locus Type
gene with protein product
Location
19q13.33
Ensembl
ENSG00000176920
Associated Conditions (3)
VITAMIN B12 PLASMA LEVEL QUANTITATIVE TRAIT LOCUS 1
Familial Otitis Media
Bombay phenotype
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1800028 | Health Risk | Conflicting classifications of pathogenicity | VITAMIN B12 PLASMA LEVEL QUANTITATIVE TRAIT LOCUS 1, Familial Otitis Media, Bombay phenotype |