FRZB Chromosome 2

Frizzled related protein
2 variants 2 Health Risk

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What This Gene Does
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. [provided by RefSeq, Apr 2010]
Gene Info
Gene Group
Secreted frizzled-related proteins
Locus Type
gene with protein product
Location
2q32.1
Ensembl
ENSG00000162998
Associated Conditions (2)
Osteoarthritis susceptibility 1
FRZB-related disorder
Key Variants
RS288326
Benign; risk factor
Osteoarthritis susceptibility 1, FRZB-related disorder, Osteoarthritis susceptibility 1
Health Risk
RS7775
Benign; risk factor
FRZB-related disorder, Osteoarthritis susceptibility 1, FRZB-related disorder
Health Risk
All Variants (2)
RSID Category Clinical Significance Conditions
RS288326 Health Risk Benign; risk factor Osteoarthritis susceptibility 1, FRZB-related disorder, Osteoarthritis susceptibility 1
RS7775 Health Risk Benign; risk factor FRZB-related disorder, Osteoarthritis susceptibility 1, FRZB-related disorder
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