FEZF1 Chromosome 7
FEZ family zinc finger 1
Upload your DNA to see your personal genotypes for variants in FEZF1.
What This Gene Does
This gene encodes a transcriptional repressor that belongs to the zinc finger double domain protein family. The encoded protein is thought to play a role in the embryonic migration of gonadotropin-releasing hormone neurons into the brain. Mutations in this gene are associated with hypogonadotropic hypogonadism-22 with anosmia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Info
Gene Group
Zinc fingers C2H2-type
Locus Type
gene with protein product
Location
7q31.32
Ensembl
ENSG00000128610
Associated Conditions (1)
Hypogonadotropic hypogonadism 22 with anosmia
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS587777739 | Health Risk | Pathogenic | Hypogonadotropic hypogonadism 22 with anosmia, Hypogonadotropic hypogonadism 22 with anosmia |
| RS587777740 | Health Risk | Pathogenic | Hypogonadotropic hypogonadism 22 with anosmia, Hypogonadotropic hypogonadism 22 with anosmia |