FEM1C Chromosome 5
Fem-1 homolog C
Upload your DNA to see your personal genotypes for variants in FEM1C.
What This Gene Does
Enables ubiquitin-like ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in cytosol and nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Ankyrin repeat domain containing
Locus Type
gene with protein product
Location
5q22.3
Ensembl
ENSG00000145780
Associated Conditions (1)
Neurodevelopmental disorder
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2531722094 | Health Risk | Likely pathogenic | Neurodevelopmental disorder, Neurodevelopmental disorder |