EIF3G Chromosome 19
Eukaryotic translation initiation factor 3 subunit G
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What This Gene Does
This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]
Gene Info
Gene Group
"RNA binding motif containing|Eukaryotic translation initiation factor 3"
Locus Type
gene with protein product
Location
19p13.2
Ensembl
ENSG00000130811
Associated Conditions (1)
Cataplexy and narcolepsy
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS3826784 | Health Risk | association | Cataplexy and narcolepsy, Cataplexy and narcolepsy |