EFNB1 Chromosome X

Ephrin B1
58 variants 58 Health Risk

Upload your DNA to see your personal genotypes for variants in EFNB1.

What This Gene Does
The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Ephrins
Locus Type
gene with protein product
Location
Xq13.1
Ensembl
ENSG00000090776
Associated Conditions (4)
Craniofrontonasal syndrome
Inborn genetic diseases
EFNB1-related disorder
Nonpapillary renal cell carcinoma
Key Variants
All Variants (58)
RSID Category Clinical Significance Conditions
RS1057519034 Health Risk Conflicting classifications of pathogenicity Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1556106222 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1556106318 Health Risk Conflicting classifications of pathogenicity
RS2080439797 Health Risk Conflicting classifications of pathogenicity Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2147976542 Health Risk Conflicting classifications of pathogenicity Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2519538222 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1057519033 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1482772814 Health Risk Likely pathogenic EFNB1-related disorder, EFNB1-related disorder
RS1556105849 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1556107856 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1602671282 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2080439314 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2080468583 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2080471329 Health Risk Likely pathogenic
RS2080471528 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2080473382 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2147973177 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2147976769 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2147976924 Health Risk Likely pathogenic
RS2519539191 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2520005872 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2520012748 Health Risk Likely pathogenic
RS2520012780 Health Risk Likely pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS104894796 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS104894801 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS104894802 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS104894803 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS104894804 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1057519035 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1064793438 Health Risk Pathogenic
RS1556096780 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1556105875 Health Risk Pathogenic Inborn genetic diseases, Inborn genetic diseases
RS1556107925 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS1569398276 Health Risk Pathogenic
RS1602670769 Health Risk Pathogenic
RS2080468475 Health Risk Pathogenic
RS2080468871 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2147973166 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2147976439 Health Risk Pathogenic
RS2147976566 Health Risk Pathogenic Craniofrontonasal syndrome, Nonpapillary renal cell carcinoma, Craniofrontonasal syndrome
RS2519538159 Health Risk Pathogenic
RS2519538409 Health Risk Pathogenic
RS2519539204 Health Risk Pathogenic
RS2519539219 Health Risk Pathogenic
RS2519539767 Health Risk Pathogenic
RS2520012737 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS2520012797 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS28935170 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS28936069 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
RS28936070 Health Risk Pathogenic Craniofrontonasal syndrome, Craniofrontonasal syndrome
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