DRD5 Chromosome 4
Dopamine receptor D5
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What This Gene Does
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Dopamine receptors
Locus Type
gene with protein product
Location
4p16.1
Ensembl
ENSG00000169676
Associated Conditions (1)
Hereditary attention deficit-hyperactivity disorder
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1967551 | Health Risk | Conflicting classifications of pathogenicity | Hereditary attention deficit-hyperactivity disorder, Hereditary attention deficit-hyperactivity disorder |