DNALI1 Chromosome 1

Dynein axonemal light intermediate chain 1

1 variant 1 Health Risk

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What This Gene Does

This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008]

Associated Conditions (1)

Spermatogenic failure 83

Key Variants

RS2522414352

Pathogenic

Spermatogenic failure 83, Spermatogenic failure 83

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS2522414352	Health Risk	Pathogenic	Spermatogenic failure 83, Spermatogenic failure 83