DENND4A Chromosome 15
DENN domain containing 4A
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What This Gene Does
This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
Gene Info
Gene Group
"DENN domain containing|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
15q22.31
Ensembl
ENSG00000174485
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1165176547 | Health Risk | Likely pathogenic | — |