CYP2J2 Chromosome 1
Cytochrome P450 family 2 subfamily J member 2
Upload your DNA to see your personal genotypes for variants in CYP2J2.
What This Gene Does
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Info
Gene Group
Cytochrome P450 family 2
Locus Type
gene with protein product
Location
1p32.1
Ensembl
ENSG00000134716
Associated Conditions (3)
Pulmonary disease
chronic obstructive
susceptibility to
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS11572191 | Health Risk | association | Pulmonary disease, chronic obstructive, susceptibility to |