CUL2 Chromosome 10
Cullin 2
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What This Gene Does
Enables ubiquitin ligase complex scaffold activity and ubiquitin protein ligase binding activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Cullins|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
10p11.21
Ensembl
ENSG00000108094
Associated Conditions (1)
Moyamoya angiopathy
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2084869461 | Health Risk | Likely pathogenic | Moyamoya angiopathy, Moyamoya angiopathy |