CREB5 Chromosome 7
CAMP responsive element binding protein 5
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What This Gene Does
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Zinc fingers C2H2-type|Basic leucine zipper proteins"
Locus Type
gene with protein product
Location
7p15.1-p14.3
Ensembl
ENSG00000146592
Associated Conditions (1)
Vascular endothelial growth factor (VEGF) inhibitor response
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS4722804 | Health Risk | association | Vascular endothelial growth factor (VEGF) inhibitor response, Vascular endothelial growth factor (VEGF) inhibitor response |