CNPY3 Chromosome 6

Canopy FGF signaling regulator 3
8 variants 8 Health Risk

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What This Gene Does
This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]
Gene Info
Gene Group
Canopy FGF signaling regulators
Locus Type
gene with protein product
Location
6p21.1
Ensembl
ENSG00000137161
Associated Conditions (2)
Developmental and epileptic encephalopathy
60
Key Variants
All Variants (8)
RSID Category Clinical Significance Conditions
RS570105218 Health Risk Conflicting classifications of pathogenicity Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS1197219692 Health Risk Likely pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS1581718297 Health Risk Likely pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS1768394971 Health Risk Likely pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS1554123960 Health Risk Pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS1554292759 Health Risk Pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS1554292820 Health Risk Pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
RS2481078839 Health Risk Pathogenic Developmental and epileptic encephalopathy, 60, Developmental and epileptic encephalopathy
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