CFAP61 Chromosome 20

Cilia and flagella associated protein 61
8 variants 8 Health Risk

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What This Gene Does
Involved in sperm flagellum assembly. Predicted to be located in motile cilium and radial spoke stalk. Predicted to be active in sperm flagellum. Implicated in spermatogenic failure 84. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Cilia and flagella associated
Locus Type
gene with protein product
Location
20p11.23
Ensembl
ENSG00000089101
Associated Conditions (1)
Spermatogenic failure 84
Key Variants
All Variants (8)
RSID Category Clinical Significance Conditions
RS199790525 Health Risk Conflicting classifications of pathogenicity
RS115717092 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
RS116775353 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
RS201899206 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
RS2515793320 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
RS2515805050 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
RS370567248 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
RS766465847 Health Risk Pathogenic Spermatogenic failure 84, Spermatogenic failure 84
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