CD22 Chromosome 19
CD22 molecule
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What This Gene Does
Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. Implicated in diffuse large B-cell lymphoma. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"CD molecules|C2-set domain containing|Sialic acid binding Ig like lectins|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
19q13.12
Ensembl
ENSG00000012124
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS140037563 | Health Risk | Conflicting classifications of pathogenicity | — |