CCDC141 Chromosome 2
Coiled-coil domain containing 141
Upload your DNA to see your personal genotypes for variants in CCDC141.
What This Gene Does
Predicted to be involved in brain development. Predicted to act upstream of or within centrosome localization and cerebral cortex radially oriented cell migration. Predicted to be located in centrosome and cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Immunoglobulin like domain containing|Spectrin repeat containing"
Locus Type
gene with protein product
Location
2q31.2
Ensembl
ENSG00000163492
Associated Conditions (2)
Hypogonadotropic hypogonadism 7 with or without anosmia
CCDC141-related disorder
Key Variants
RS1391287036
Conflicting classifications of pathogenicity
Health Risk
RS139365189
Conflicting classifications of pathogenicity
Health Risk
RS141786551
Conflicting classifications of pathogenicity
Health Risk
RS141939661
Conflicting classifications of pathogenicity
Hypogonadotropic hypogonadism 7 with or without anosmia, CCDC141-related disorder, Hypogonadotropic hypogonadism 7 with or without anosmia
Health Risk
RS142479179
Conflicting classifications of pathogenicity
Health Risk
RS143025382
Conflicting classifications of pathogenicity
CCDC141-related disorder, CCDC141-related disorder
Health Risk
RS148275217
Conflicting classifications of pathogenicity
Health Risk
RS148579179
Conflicting classifications of pathogenicity
Health Risk
RS150440298
Conflicting classifications of pathogenicity
Health Risk
RS540836199
Conflicting classifications of pathogenicity
CCDC141-related disorder, CCDC141-related disorder
Health Risk
RS761023328
Conflicting classifications of pathogenicity
Health Risk
All Variants (11)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1391287036 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS139365189 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS141786551 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS141939661 | Health Risk | Conflicting classifications of pathogenicity | Hypogonadotropic hypogonadism 7 with or without anosmia, CCDC141-related disorder, Hypogonadotropic hypogonadism 7 with or without anosmia |
| RS142479179 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS143025382 | Health Risk | Conflicting classifications of pathogenicity | CCDC141-related disorder, CCDC141-related disorder |
| RS148275217 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS148579179 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS150440298 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS540836199 | Health Risk | Conflicting classifications of pathogenicity | CCDC141-related disorder, CCDC141-related disorder |
| RS761023328 | Health Risk | Conflicting classifications of pathogenicity | — |