CALHM1 Chromosome 10

Calcium homeostasis modulator 1

1 variant 1 Health Risk

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What This Gene Does

This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010]

Gene Info

Gene Group

Calcium homeostasis modulators

Locus Type

gene with protein product

Location

10q24.33

Ensembl

ENSG00000185933

Key Variants

RS371900329

Likely pathogenic

Health Risk

All Variants (1)

RSID	Category	Clinical Significance	Conditions
RS371900329	Health Risk	Likely pathogenic	—