BRDT Chromosome 1
Bromodomain testis associated
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What This Gene Does
BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Info
Gene Group
"Bromodomain and extra-terminal domain family|Bromodomain containing"
Locus Type
gene with protein product
Location
1p22.1
Ensembl
ENSG00000137948
Associated Conditions (1)
Premature ovarian failure
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1188709614 | Health Risk | Pathogenic | Premature ovarian failure, Premature ovarian failure |