AURKB Chromosome 17
Aurora kinase B
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What This Gene Does
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
Gene Info
Gene Group
"Protein phosphatase 1 regulatory subunits|Chromosomal passenger complex|Aurora kinase family"
Locus Type
gene with protein product
Location
17p13.1
Ensembl
ENSG00000178999
Associated Conditions (1)
NK-cell enteropathy
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1597343914 | Health Risk | Likely pathogenic | NK-cell enteropathy, NK-cell enteropathy |