AURKA Chromosome 20
Aurora kinase A
Upload your DNA to see your personal genotypes for variants in AURKA.
What This Gene Does
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
"Protein phosphatase 1 regulatory subunits|Aurora kinase family"
Locus Type
gene with protein product
Location
20q13.2
Ensembl
ENSG00000087586
Associated Conditions (1)
Multiple myeloma
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1455074519 | Health Risk | Likely pathogenic | Multiple myeloma, Multiple myeloma |