ASAP3 Chromosome 1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
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What This Gene Does
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Gene Info
Gene Group
"ArfGAPs|Ankyrin repeat domain containing|BAR-PH domain containing"
Locus Type
gene with protein product
Location
1p36.12
Ensembl
ENSG00000088280
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS137927599 | Health Risk | Conflicting classifications of pathogenicity | — |