ARIH1 Chromosome 15

Ariadne RBR E3 ubiquitin protein ligase 1

2 variants 2 Health Risk

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What This Gene Does

Enables enzyme binding activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Involved in protein ubiquitination. Located in several cellular components, including Lewy body; cullin-RING ubiquitin ligase complex; and nuclear body. [provided by Alliance of Genome Resources, Jul 2025]

Gene Info

Gene Group

"Ring finger proteins|RBR E3 ubiquitin ligases"

Locus Type

gene with protein product

Location

15q24.1

Ensembl

ENSG00000166233

Associated Conditions (1)

Aortic aneurysm

Key Variants