ARFGEF3 Chromosome 6
ARFGEF family member 3
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What This Gene Does
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Predicted to be located in transport vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Protein phosphatase 1 regulatory subunits|Armadillo like helical domain containing|ArfGEF family"
Locus Type
gene with protein product
Location
6q23.3-q24.1
Ensembl
ENSG00000112379
Associated Conditions (4)
ARFGEF3-related disorder
Thyroid cancer
nonmedullary
1
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS116596107 | Health Risk | Conflicting classifications of pathogenicity | ARFGEF3-related disorder, Thyroid cancer, nonmedullary |