APOA2 Chromosome 1
Apolipoprotein A2
Upload your DNA to see your personal genotypes for variants in APOA2.
What This Gene Does
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
Gene Info
Gene Group
Apolipoproteins
Locus Type
gene with protein product
Location
1q23.3
Ensembl
ENSG00000158874
Associated Conditions (1)
APOLIPOPROTEIN A-II DEFICIENCY
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS2525759209 | Health Risk | Likely pathogenic | — |
| RS771259264 | Health Risk | Pathogenic | APOLIPOPROTEIN A-II DEFICIENCY, APOLIPOPROTEIN A-II DEFICIENCY |