AMER3 Chromosome 2
APC membrane recruitment protein 3
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What This Gene Does
Predicted to enable beta-catenin binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Gene Info
Gene Group
APC membrane recruitment proteins
Locus Type
gene with protein product
Location
2q21.1
Ensembl
ENSG00000178171
Associated Conditions (1)
Esophageal atresia/tracheoesophageal fistula
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS768719549 | Health Risk | Likely pathogenic | Esophageal atresia/tracheoesophageal fistula, Esophageal atresia/tracheoesophageal fistula |