ALPK2 Chromosome 18
Alpha kinase 2
Upload your DNA to see your personal genotypes for variants in ALPK2.
What This Gene Does
Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in several processes, including epicardium morphogenesis; heart development; and negative regulation of Wnt signaling pathway involved in heart development. Acts upstream of or within regulation of gene expression. Located in basolateral plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"I-set domain containing|Alpha kinases"
Locus Type
gene with protein product
Location
18q21.31-q21.32
Ensembl
ENSG00000198796
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS200620811 | Health Risk | Conflicting classifications of pathogenicity | — |