ADGRA3 Chromosome 4
Adhesion G protein-coupled receptor A3
Upload your DNA to see your personal genotypes for variants in ADGRA3.
What This Gene Does
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012]
Gene Info
Gene Group
"I-set domain containing|Adhesion G protein-coupled receptors, subfamily A"
Locus Type
gene with protein product
Location
4p15.2
Ensembl
ENSG00000152990
Associated Conditions (2)
Retinal dystrophy
ADGRA3-related disorder
Key Variants
RS1322803235
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS138525539
Conflicting classifications of pathogenicity
ADGRA3-related disorder, ADGRA3-related disorder
Health Risk
RS138542858
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS138696398
Conflicting classifications of pathogenicity
Health Risk
RS141619991
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS146569496
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS146897125
Conflicting classifications of pathogenicity
Health Risk
RS200835396
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS201521604
Conflicting classifications of pathogenicity
Health Risk
RS201588033
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS370347164
Conflicting classifications of pathogenicity
Retinal dystrophy, Retinal dystrophy
Health Risk
RS372946484
Conflicting classifications of pathogenicity
Health Risk
All Variants (16)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1322803235 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS138525539 | Health Risk | Conflicting classifications of pathogenicity | ADGRA3-related disorder, ADGRA3-related disorder |
| RS138542858 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS138696398 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS141619991 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS146569496 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS146897125 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200835396 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS201521604 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS201588033 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS370347164 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS372946484 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS761890075 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS768819559 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS775038374 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |
| RS780809068 | Health Risk | Conflicting classifications of pathogenicity | Retinal dystrophy, Retinal dystrophy |