Hereditary Cancer

Cancer 324 variants 19 genes

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Associated Genes (19)

SH2B3 MSH2 BRCA1 FBXO11;MSH6 MSH6 MLH1 BRCA2 PMS2 MET PALB2 NBN APC FANCM RAD51 RET CDKN2A NF1 MUTYH WT1

Associated Variants (324)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS202080221	SH2B3	—	—	exploratory
RS63750124	MSH2	—	—	strong
RS80357257	BRCA1	—	—	strong
RS80357001	BRCA1	—	—	strong
RS2020906	FBXO11;MSH6	—	—	strong
RS34938432	MSH6	—	—	strong
RS191109849	MSH6	—	—	strong
RS41557217	MSH6	—	—	strong
RS267608051	MSH6	—	—	strong
RS56198082	MLH1	—	—	strong
RS63751467	MLH1	—	—	strong
RS63750760	MLH1	—	—	strong
RS63750796	MLH1	—	—	strong
RS17217723	MSH2	—	—	strong
RS80359251	BRCA2	—	—	strong
RS149202766	PMS2	—	—	strong
RS201274041	MET	—	—	strong
RS80358989	BRCA2	—	—	strong
RS431825362	BRCA2	—	—	strong
RS200620434	PALB2	—	—	strong
RS515726072	PALB2	—	—	strong
RS45594034	PALB2	—	—	strong
RS61754796	NBN	—	—	strong
RS587779796	APC	—	—	strong
RS200587641	APC	—	—	strong
RS1023555775	FANCM	—	—	strong
RS143796828	APC	—	—	strong
RS121917739	RAD51	—	—	strong
RS34682185	RET	—	—	strong
RS377767416	RET	—	—	strong
RS146838520	RET	—	—	strong
RS55808233	BRCA1	—	—	strong
RS80358439	BRCA2	—	—	strong
RS80358531	BRCA2	—	—	strong
RS397507350	BRCA2	—	—	strong
RS80359078	BRCA2	—	—	strong
RS397507407	BRCA2	—	—	strong
RS148725540	APC	—	—	strong
RS104894097	CDKN2A	—	—	strong
RS149945495	MSH6	—	—	strong
RS17881753	NF1	—	—	strong
RS201671325	PMS2	—	—	strong
RS150792276	MUTYH	—	—	strong
RS138089183	MUTYH	—	—	strong
RS142059681	WT1	—	—	strong
RS68071147	BRCA2	—	—	strong
RS80358782	BRCA2	—	—	strong
RS80358960	BRCA2	—	—	strong
RS80359018	BRCA2	—	—	strong
RS80359194	BRCA2	—	—	strong

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