Familial Pancreatic Carcinoma

Cancer 138 variants 36 genes

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Associated Genes (36)

BRCA1 CARD9 STK11 CEP78 KRAS COX20 SMAD4 BRCA2 PALB2 DVL1 DNAJC21 TP53 GLDC CYP4V2 REL LRSAM1 CWC27 MBD4 EXOSC9 KIAA0825 ATR LRPPRC GFM1 PTCH1 PTPN22 FREM1 CDKN2A IL17F CFTR IFIH1 SETX DYSF ADAR DIAPH1 MAK DUS4L-BCAP29;COG5;DUS4L

Associated Variants (138)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS2053516476	BRCA1	—	—	strong
RS114895119	CARD9	—	—	strong
RS759090799	STK11	—	—	strong
RS745750156	CEP78	—	—	strong
RS1057519725	KRAS	—	—	strong
RS367956888	COX20	—	—	strong
RS773615487	SMAD4	—	—	strong
RS1060502421	BRCA2	—	—	strong
RS1060504718	PALB2	—	—	strong
RS376280361	STK11	—	—	strong
RS142925511	DVL1	—	—	strong
RS182094106	DNAJC21	—	—	strong
RS1597374098	TP53	—	—	strong
RS150095531	GLDC	—	—	strong
RS1300138505	CYP4V2	—	—	strong
RS142878172	REL	—	—	strong
RS2053470202	BRCA1	—	—	strong
RS76153575	LRSAM1	—	—	strong
RS767210188	CWC27	—	—	strong
RS2137531137	BRCA2	—	—	strong
RS2137476122	BRCA2	—	—	strong
RS78782061	MBD4	—	—	strong
RS568625247	STK11	—	—	strong
RS151134983	EXOSC9	—	—	strong
RS766167375	KIAA0825	—	—	strong
RS374006397	STK11	—	—	strong
RS797045404	ATR	—	—	strong
RS144826521	LRPPRC	—	—	strong
RS201685981	GFM1	—	—	strong
RS186008764	PTCH1	—	—	strong
RS45537237	PALB2	—	—	strong
RS56048322	PTPN22	—	—	strong
RS41298151	FREM1	—	—	strong
RS764244718	CDKN2A	—	—	strong
RS864622401	BRCA2	—	—	strong
RS375185293	SMAD4	—	—	strong
RS864622488	STK11	—	—	strong
RS117796773	IL17F	—	—	strong
RS1805177	CFTR	—	—	strong
RS760792501	BRCA2	—	—	strong
RS755210880	STK11	—	—	strong
RS35337543	IFIH1	—	—	strong
RS61742937	SETX	—	—	strong
RS886040125	BRCA1	—	—	strong
RS750356247	DYSF	—	—	strong
RS190881240	ADAR	—	—	strong
RS375168014	GFM1	—	—	strong
RS193036129	DIAPH1	—	—	strong
RS76972797	MAK	—	—	strong
RS145603444	DUS4L-BCAP29;COG5;DUS4L	—	—	strong

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