Familial Colorectal Cancer
Cancer
56 variants
12 genes
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Associated Genes (12)
POLE
POLD1
MSH2
MLH1
GREM1
MUTYH
MT-CO1
TP53
PLA2G2A
APC
MSH6
GALNT12
Associated Variants (56)
RSID
Gene
Risk Allele
Odds Ratio
Evidence
RS2050395
—
—
5.33
moderate
RS7071839
—
—
5.33
moderate
RS12723298
—
—
4.04
moderate
RS10495462
—
—
4.04
moderate
RS10889978
—
—
3.78
moderate
RS3819842
—
—
3.78
moderate
RS4316701
—
—
2.55
moderate
RS10162671
—
—
2.55
moderate
RS2001651
—
—
2.42
moderate
RS6587119
—
—
2.42
moderate
RS9855367
—
—
2.25
moderate
RS9861579
—
—
2.25
moderate
RS771490182
POLE
—
—
strong
RS762626359
POLE
—
—
strong
RS777002868
POLE
—
—
strong
RS115558715
POLE
—
—
strong
RS777390504
POLE
—
—
strong
RS113998091
POLE
—
—
strong
RS1060500808
POLE
—
—
strong
RS1040524947
POLD1
—
—
strong
RS1451513451
POLE
—
—
strong
RS1568639764
POLD1
—
—
strong
RS1667575488
MSH2
—
—
strong
RS2085261656
MLH1
—
—
strong
RS111262341
GREM1
—
—
strong
RS63750582
MSH2
—
—
strong
RS36053993
MUTYH
—
—
strong
RS121908380
MUTYH
—
—
strong
RS281865417
MT-CO1
—
—
strong
RS267606884
MT-CO1
—
—
strong
RS121912659
TP53
—
—
strong
RS121912665
TP53
—
—
strong
RS587776800
PLA2G2A
—
—
strong
RS200495564
MUTYH
—
—
strong
RS79512956
APC
—
—
strong
RS79323615
APC
—
—
strong
RS74953290
APC
—
—
strong
RS267608078
MSH6
—
—
strong
RS1801155
APC
—
—
strong
RS111866410
APC
—
—
strong
RS200587641
APC
—
—
strong
RS587778536
MUTYH
—
—
strong
RS587783057
MUTYH
—
—
strong
RS183981750
GALNT12
—
—
strong
RS151273553
POLE
—
—
strong
RS144979965
POLD1
—
—
strong
RS41554817
POLD1
—
—
strong
RS141976385
POLD1
—
—
strong
RS143076166
POLD1
—
—
strong
RS879254126
POLE
—
—
strong
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