Early Onset Severe Obesity

Metabolic 38 variants 14 genes

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Associated Genes (14)

MYT1L MC4R PHIP POMC LEP KIDINS220 LEPR BBS9 VPS13B BBS2 MKKS BBS10 ALMS1 MKS1

Associated Variants (38)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS201761335	MYT1L	—	—	strong
RS1057517991	MC4R	—	—	strong
RS13447339	MC4R	—	—	strong
RS370479598	MC4R	—	—	strong
RS549442687	MC4R	—	—	strong
RS565098856	PHIP	—	—	strong
RS771126523	PHIP	—	—	strong
RS8192606	POMC	—	—	strong
RS62481073	LEP	—	—	strong
RS201077051	KIDINS220	—	—	strong
RS747681609	MC4R	—	—	strong
RS13447332	MC4R	—	—	strong
RS2100932956	LEPR	—	—	strong
RS775189420	KIDINS220	—	—	strong
RS767119807	KIDINS220	—	—	strong
RS151102515	MC4R	—	—	strong
RS1216420598	PHIP	—	—	strong
RS142837166	MC4R	—	—	strong
RS2536369263	BBS9	—	—	strong
RS73273219	VPS13B	—	—	strong
RS137852858	BBS9	—	—	strong
RS121908175	BBS2	—	—	strong
RS753856820	POMC	—	—	strong
RS121913559	MC4R	—	—	strong
RS121913560	MC4R	—	—	strong
RS121913562	MC4R	—	—	strong
RS13447331	MC4R	—	—	strong
RS74315394	MKKS	—	—	strong
RS52804924	MC4R	—	—	strong
RS549625604	BBS10	—	—	strong
RS35676114	BBS10	—	—	strong
RS376306240	BBS2	—	—	strong
RS45501594	ALMS1	—	—	strong
RS11373	BBS2	—	—	strong
RS201619500	MKS1	—	—	strong
RS145419141	VPS13B	—	—	strong
RS142647085	LEPR	—	—	strong
RS145651189	LEPR	—	—	strong